Skip to main content

Key Points

  • XANAX® (alprazolam), is the most commonly prescribed benzodiazepine for the treatment of Generalized Anxiety Disorder (GAD) and other panic disorders
  • It works with the GABA-A receptors in our brain and spinal cord to calm our central nervous systems.
  • Common side effects of XANAX® may include the inability to concentrate, poor coordination, gastrointestinal issues, stuffy nose, and swelling of hands or feet.
  • XANAX® can cause a dependency, and its abuse is classified as a sedative use disorder under the DSM-5.
  • XANAX® should not be taken by pregnant or nursing women.
  • Mixing XANAX® with opiates, alcohol, cough and cold medications and some prescriptions could lead to health emergencies and/or death.

Close-up of Xanax tablets on table

Doctors may prescribe Xanax to provide short-term relief from severe anxiety or recurring panic attacks. Although it can calm symptoms quickly, the medication can also cause drowsiness, dependence, and potentially dangerous withdrawal symptoms. [1]

This article provides general educational information and does not replace professional medical advice. Never reduce or discontinue alprazolam without guidance from the healthcare professional managing your treatment.

What Is Xanax and Why Prescribed?

XANAX® contains alprazolam, a medication belonging to the benzodiazepine class. Other medications in this group include lorazepam, diazepam, and clonazepam. Benzodiazepines reduce excessive activity within the central nervous system.

Immediate-release XANAX® is approved for the acute treatment of generalized anxiety disorder and the treatment of panic disorder, with or without agoraphobia, in adults. XANAX XR®, its extended-release formulation, is approved for treating panic disorder in adults.

Alprazolam is a Schedule IV controlled substance in the United States. It has accepted medical uses but also carries risks of misuse, physical dependence, and addiction.

How Xanax Affects the Nervous System

XANAX® enhances the activity of gamma-aminobutyric acid, commonly called GABA. This neurotransmitter reduces signaling between nerve cells and helps calm excessive activity in the brain.

By strengthening GABA’s effects, alprazolam may reduce anxiety, tension, restlessness, and panic symptoms. The medication may also slow thinking, reduce alertness, and cause drowsiness or poor coordination.

Some clinicians prescribe alprazolam for conditions outside its FDA-approved uses. This is called off-label prescribing. XANAX® should only be used for the condition and in the manner directed by a qualified prescriber.

How to Take Xanax More Safely

Take XANAX® exactly as prescribed. Do not increase the dose, take it more often, or continue treatment longer than directed. Never share the medication with another person. [2]

Immediate-release tablets can generally be taken with or without food. Extended-release tablets should be swallowed whole. Crushing, chewing, or dividing XANAX XR® can release the medication too quickly.

Avoid alcohol and do not combine XANAX® with opioids, sleeping pills, muscle relaxants, or other sedating substances unless a healthcare professional has approved the combination. Do not drive or operate machinery until you understand how the medication affects you.

Common Xanax Dosages and Important Limits

Dosage depends on the condition, formulation, age, health, other medications, and individual response. The figures below are FDA-labeled starting doses and must not be treated as personal dosing instructions.

Condition Adult starting dosage Geriatric starting dosage
Generalized anxiety disorder Immediate-release XANAX®: 0.25 mg to 0.5 mg three times daily. The maximum recommended dosage is 4 mg daily in divided doses. Immediate-release XANAX®: 0.25 mg two or three times daily.
Panic disorder Immediate-release XANAX®: 0.5 mg three times daily. Any increase must be directed by the prescriber. Immediate-release XANAX®: 0.25 mg two or three times daily.
Panic disorder XANAX XR®: 0.5 mg to 1 mg once daily, preferably in the morning. XANAX XR®: 0.5 mg once daily.

Older adults may process alprazolam more slowly and can be especially sensitive to its sedating effects. Liver problems and certain drug interactions may also require a lower dose. [3]

Never use this table to start, increase, reduce, or discontinue XANAX® independently. Dosing decisions must be made by the healthcare professional responsible for your treatment.

Benefits and Possible Side Effects of Xanax

XANAX® may provide relatively fast relief from severe anxiety or panic symptoms. This can make it helpful during the acute treatment of certain anxiety disorders when used under medical supervision.

However, its calming effects can also cause drowsiness, memory problems, reduced alertness, and impaired coordination. These reactions may increase the risk of falls, driving accidents, and other injuries.

Prescribers generally aim to use the lowest effective dose and periodically evaluate whether continued treatment is necessary. The potential benefits must always be weighed against the risks of side effects, dependence, and withdrawal.

Common Side Effects You May Experience

The type and severity of side effects can depend on the dose, treatment duration, formulation, age, health, and use of other substances.

Common or clinically recognized XANAX® side effects include:

  • Drowsiness or tiredness
  • Dizziness or light-headedness
  • Impaired balance or coordination
  • Slowed thinking
  • Reduced mental alertness
  • Memory difficulties
  • Trouble concentrating
  • Slurred speech
  • Headaches
  • Nausea or vomiting
  • Constipation or diarrhea
  • Dry mouth
  • Appetite or weight changes
  • Muscle weakness
  • Changes in sexual interest
  • Irritability
  • Sleep problems

Tell your healthcare provider if these effects persist, worsen, or interfere with daily activities.

Serious Side Effects Requiring Immediate Medical Care

Some alprazolam reactions can become life-threatening. Seek emergency medical help if you notice:

  • Slow, shallow, or difficult breathing
  • Extreme sleepiness
  • Inability to wake the person
  • Severe confusion
  • Loss of consciousness
  • Fainting
  • Seizures
  • Hallucinations
  • Severe agitation
  • Unusual behavior
  • Suicidal thoughts or actions
  • Swelling around the face or throat
  • Difficulty swallowing
  • Coma

Call emergency services immediately if an overdose is suspected. This is particularly important when XANAX® has been combined with opioids, alcohol, or another sedating substance.

Pregnant woman consulting medication instructions for Xanax due to possible side effects

Dangerous Xanax Interactions With Other Substances

Combining XANAX® with opioids can cause profound sedation, respiratory depression, coma, or death. Alcohol, sleeping medications, muscle relaxants, sedating antihistamines, and other central nervous system depressants may produce similar additive effects.

Certain medications can also change how quickly the body processes alprazolam. Strong CYP3A inhibitors, including ketoconazole and itraconazole, can significantly increase alprazolam concentrations and are generally contraindicated.

Tell your doctor and pharmacist about every prescription medication, over-the-counter product, vitamin, and supplement you use. Do not start or stop another medicine without professional advice.

Xanax Use During Pregnancy and Associated Risks

Tell your healthcare provider if you are pregnant, planning to become pregnant, or discover that you are pregnant while taking XANAX®. Alprazolam crosses the placenta and may affect the developing baby. [4]

Benzodiazepine exposure during the later stages of pregnancy may cause sedation or withdrawal in a newborn. Possible problems include poor muscle tone, feeding difficulties, breathing problems, irritability, and abnormal sleep.

Do not abruptly discontinue XANAX® after learning that you are pregnant. Sudden withdrawal may be dangerous. A healthcare professional should assess the benefits and risks before developing a treatment or tapering plan.

Xanax Use While Breastfeeding an Infant

Alprazolam can pass into human breast milk. Infants exposed to benzodiazepines through breast milk may experience sedation, poor feeding, insufficient weight gain, or withdrawal symptoms.

The official XANAX® prescribing information advises that breastfeeding is not recommended during treatment. A healthcare provider can explain alternative medications or feeding options.

Do not change your medication or feeding plan without consulting the healthcare professionals responsible for your care and your baby’s health.

Can Xanax Misuse Lead to Addiction?

Yes. XANAX® can be misused and may contribute to addiction. Misuse includes taking a larger dose than prescribed, using the medication more often, taking someone else’s prescription, or combining it with other substances.

Physical dependence may also develop during prescribed treatment. Dependence means the body has adapted to alprazolam and may produce withdrawal symptoms when the dosage is reduced or stopped. Physical dependence is not automatically the same as addiction.

The risk generally increases with higher doses and longer treatment periods. However, dependence can sometimes develop after relatively short-term use, including when the medication has been taken as prescribed.

Warning Signs of Problematic Xanax Use

Signs that XANAX® use may have become harmful include:

  • Taking more than the prescribed amount
  • Using doses earlier than directed
  • Obtaining prescriptions from multiple providers
  • Buying or borrowing alprazolam
  • Experiencing strong cravings
  • Trying unsuccessfully to reduce use
  • Needing larger amounts for the same effect
  • Spending considerable time obtaining or using XANAX®
  • Continuing despite health or relationship problems
  • Neglecting responsibilities because of use
  • Combining XANAX® with alcohol or opioids
  • Experiencing withdrawal after missing a dose

Other warning signs may include unexplained sedation, memory gaps, slurred speech, poor coordination, secretive behavior, or significant changes in daily functioning. A clinical assessment is needed because some of these signs can have other causes.

Treatment and Recovery From Xanax Misuse

Stopping XANAX® suddenly after regular use can be dangerous. Withdrawal may cause severe anxiety, insomnia, sweating, tremors, agitation, perceptual changes, depression, or seizures. Some people experience symptoms lasting for an extended period.

Treatment should begin with a professional assessment. Depending on the person’s needs, care may include medically supervised detoxification, residential treatment, partial hospitalization, intensive outpatient care, individual counseling, group therapy, and family support.

Treatment may also address depression, anxiety, trauma, or other mental health concerns occurring alongside substance use. [5] The recommended level of care depends on the dose, duration of use, other substances involved, withdrawal history, physical health, and available support.

Xanax Treatment Support at Ocean Recovery

At Ocean Recovery, we support people whose XANAX® use has begun affecting their health, relationships, responsibilities, or daily life. We understand that stopping suddenly can be dangerous, especially after regular or high-dose use.

We provide structured treatment for benzodiazepine misuse and related substance use concerns. Our services may include supervised withdrawal support, residential care, therapy, and treatment for co-occurring mental health conditions.

Contact us to speak privately with our admissions team. We can discuss your circumstances, explain our treatment options, and help you determine an appropriate next step.

Frequently Asked Questions About Xanax Use

Is Xanax Classified as a Controlled Substance?

Yes. XANAX® contains alprazolam, which is classified as a Schedule IV controlled substance in the United States. It must be prescribed by an appropriately licensed healthcare professional. Federal regulations generally allow a Schedule IV prescription to be refilled no more than five times within six months. State laws and clinical policies may impose additional restrictions.

How Commonly Is Xanax Prescribed for Anxiety?

Alprazolam is widely prescribed for anxiety and panic symptoms. Immediate-release XANAX® is FDA-approved for the acute treatment of generalized anxiety disorder and the treatment of panic disorder in adults. XANAX XR® is approved for panic disorder in adults. Because alprazolam can cause sedation, dependence, and withdrawal, clinicians may recommend other medications or therapy for longer-term treatment.

Why Can Stopping Xanax Become So Difficult?

Regular XANAX® use can cause physical dependence. When the medication is stopped suddenly or reduced too quickly, the nervous system may struggle to adjust. Withdrawal symptoms can include anxiety, insomnia, sweating, tremors, appetite changes, depression, unusual sensations, and seizures. A healthcare provider should create and supervise an individualized taper.

What Happens After Missing a Xanax Dose?

Take the missed dose when you remember unless it is almost time for the next scheduled dose. If the next dose is approaching, skip the missed dose and continue with the regular schedule. Never take two doses together to compensate for a missed dose. Contact your healthcare provider if missing a dose causes withdrawal symptoms or if you are unsure what to do.

Disclaimer

This article provides general educational information and does not replace professional medical advice. Speak with your prescribing clinician before changing your medication or alcohol use.

Reference 

  1. https://labeling.pfizer.com/showlabeling.aspx?id=547
  2. https://labeling.pfizer.com/ShowLabeling.aspx?id=547&section=MedGuide
  3. https://labeling.pfizer.com/showlabeling.aspx?id=547
  4. https://labeling.pfizer.com/showlabeling.aspx?id=547
  5. https://www.asam.org/asam-criteria

Frequently Asked Questions Related To "What Is Xanax"

According to the Drug Enforcement Administration (DEA), XANAX® is a Schedule IV controlled substance. A physician or therapist must prescribe Xanax®; prescriptions are only good for six months and can only be refilled up to five times.

XANAX®, also sold as alprazolam, is not only the most commonly prescribed benzodiazepine [5], but it is also the most commonly prescribed psychotropic medication in the U.S. It is an effective treatment for generalized anxiety disorder, panic disorder, and other related disorders.

Like other benzodiazepine medications, reducing or stopping XANAX® can result in withdrawal symptoms, including anxiety, sweating, loss of appetite, sleep problems, and, in rare and severe cases, seizures. By working with your doctor or pharmacist, you can taper off your dosage and avoid many of these withdrawal symptoms.

There is a Better Way to Live. It's Time to Get the Help You Deserve.

Take the first step in getting your life back. Speak with our admissions team today.
Contact Us

OCEAN RECOVERY EDITORIAL GUIDELINES

The internet contains a vast amount of misinformation, but when it comes to your health only peer reviewed, research centered data matters. At Ocean Recovery, all content published throughout our website has been rigorously medically reviewed by a doctorate level clinician, and cross checked for medical accuracy. Our editorial process helps our readers trust that the information they are consuming is factual and based upon scientific data. Your health is our top priority, find out more about how we safeguard the integrity of information on our website. Read More About Our Process

Ocean Recovery has sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations for our reference. We avoid using tertiary references as our sources. You can learn more about how we source our references by reading our Editorial Policy.

[1] StatPearls – NCBI Bookshelf. (n.d.-a). Alprazolam. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK538165/ on May 15, 2023.
[2] StatPearls – NCBI Bookshelf. Physiology, GABA (n.d.-b). Retrieved from
https://www.ncbi.nlm.nih.gov/books/NBK513311/ on May 15, 2023.
[3]CIV- Food and Drug Administration(n.d.). XANAX alprazolam tablets. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018276s045lbl.pdf on May 15, 2023.
[4] Frontiers in pharmacology. Pregnancy and Neonatal Outcomes After Exposure to Alprazolam in Pregnancy. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081603/ on May 15, 2023.
[5] Ait-Daoud, N., Hamby, A. S., Sharma, S., & Blevins, D. (2018). Journal of addiction medicine. A review of Alprazolam use, misuse, and withdrawal. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846112/ on May 15, 2023.

Last medically reviewed September 14, 2023.

Secret Link